( ! ) Fatal error: Allowed memory size of 134217728 bytes exhausted (tried to allocate 5242880 bytes) in C:\wamp64\www\cidei\wp-content\plugins\dk-pdf\lib\packages\Mpdf\CssManager.php on line 2225
Call Stack
#TimeMemoryFunctionLocation
10.0002447760{main}( )...\index.php:0
20.0003448112require( 'C:\wamp64\www\cidei\wp-blog-header.php )...\index.php:17
31.876784146264wp( $query_vars = ??? )...\wp-blog-header.php:16
41.876784146296WP->main( $query_args = '' )...\functions.php:1342
51.886784301168do_action_ref_array( $hook_name = 'wp', $args = [0 => class WP { public $public_query_vars = [...]; public $private_query_vars = [...]; public $extra_query_vars = [...]; public $query_vars = [...]; public $query_string = 'paged=2&tag=ana-margarida-cunha&pdf=9370'; public $request = 'tag/ana-margarida-cunha/page/2'; public $matched_rule = 'tag/([^/]+)/page/?([0-9]{1,})/?$'; public $matched_query = 'tag=ana-margarida-cunha&paged=2'; public $did_permalink = TRUE }] )...\class-wp.php:835
61.886784301168WP_Hook->do_action( $args = [0 => class WP { public $public_query_vars = [...]; public $private_query_vars = [...]; public $extra_query_vars = [...]; public $query_vars = [...]; public $query_string = 'paged=2&tag=ana-margarida-cunha&pdf=9370'; public $request = 'tag/ana-margarida-cunha/page/2'; public $matched_rule = 'tag/([^/]+)/page/?([0-9]{1,})/?$'; public $matched_query = 'tag=ana-margarida-cunha&paged=2'; public $did_permalink = TRUE }] )...\plugin.php:565
71.886784301168WP_Hook->apply_filters( $value = '', $args = [0 => class WP { public $public_query_vars = [...]; public $private_query_vars = [...]; public $extra_query_vars = [...]; public $query_vars = [...]; public $query_string = 'paged=2&tag=ana-margarida-cunha&pdf=9370'; public $request = 'tag/ana-margarida-cunha/page/2'; public $matched_rule = 'tag/([^/]+)/page/?([0-9]{1,})/?$'; public $matched_query = 'tag=ana-margarida-cunha&paged=2'; public $did_permalink = TRUE }] )...\class-wp-hook.php:348
81.886884301848Dinamiko\DKPDF\PDF\PDFModule->Dinamiko\DKPDF\PDF\{closure:C:\wamp64\www\cidei\wp-content\plugins\dk-pdf\modules\PDF\PDFModule.php:23-28}( $wp = class WP { public $public_query_vars = [0 => 'm', 1 => 'p', 2 => 'posts', 3 => 'w', 4 => 'cat', 5 => 'withcomments', 6 => 'withoutcomments', 7 => 's', 8 => 'search', 9 => 'exact', 10 => 'sentence', 11 => 'calendar', 12 => 'page', 13 => 'paged', 14 => 'more', 15 => 'tb', 16 => 'pb', 17 => 'author', 18 => 'order', 19 => 'orderby', 20 => 'year', 21 => 'monthnum', 22 => 'day', 23 => 'hour', 24 => 'minute', 25 => 'second', 26 => 'name', 27 => 'category_name', 28 => 'tag', 29 => 'feed', 30 => 'author_name', 31 => 'pagename', 32 => 'page_id', 33 => 'error', 34 => 'attachment', 35 => 'attachment_id', 36 => 'subpost', 37 => 'subpost_id', 38 => 'preview', 39 => 'robots', 40 => 'favicon', 41 => 'taxonomy', 42 => 'term', 43 => 'cpage', 44 => 'post_type', 45 => 'embed', 46 => 'post_format', 47 => 'rest_route', 48 => 'sitemap', 49 => 'sitemap-subtype', 50 => 'sitemap-stylesheet', 51 => 'entries', 52 => 'pdf', 53 => 'sitemap', 54 => 'sitemap_n', 55 => 'yoast-sitemap-xsl']; public $private_query_vars = [0 => 'offset', 1 => 'posts_per_page', 2 => 'posts_per_archive_page', 3 => 'showposts', 4 => 'nopaging', 5 => 'post_type', 6 => 'post_status', 7 => 'category__in', 8 => 'category__not_in', 9 => 'category__and', 10 => 'tag__in', 11 => 'tag__not_in', 12 => 'tag__and', 13 => 'tag_slug__in', 14 => 'tag_slug__and', 15 => 'tag_id', 16 => 'post_mime_type', 17 => 'perm', 18 => 'comments_per_page', 19 => 'post__in', 20 => 'post__not_in', 21 => 'post_parent', 22 => 'post_parent__in', 23 => 'post_parent__not_in', 24 => 'title', 25 => 'fields']; public $extra_query_vars = []; public $query_vars = ['paged' => '2', 'tag' => 'ana-margarida-cunha', 'pdf' => '9370']; public $query_string = 'paged=2&tag=ana-margarida-cunha&pdf=9370'; public $request = 'tag/ana-margarida-cunha/page/2'; public $matched_rule = 'tag/([^/]+)/page/?([0-9]{1,})/?$'; public $matched_query = 'tag=ana-margarida-cunha&paged=2'; public $did_permalink = TRUE } )...\class-wp-hook.php:324
91.888584382208Dinamiko\DKPDF\PDF\Generator->handle_pdf_request( $wp = class WP { public $public_query_vars = [0 => 'm', 1 => 'p', 2 => 'posts', 3 => 'w', 4 => 'cat', 5 => 'withcomments', 6 => 'withoutcomments', 7 => 's', 8 => 'search', 9 => 'exact', 10 => 'sentence', 11 => 'calendar', 12 => 'page', 13 => 'paged', 14 => 'more', 15 => 'tb', 16 => 'pb', 17 => 'author', 18 => 'order', 19 => 'orderby', 20 => 'year', 21 => 'monthnum', 22 => 'day', 23 => 'hour', 24 => 'minute', 25 => 'second', 26 => 'name', 27 => 'category_name', 28 => 'tag', 29 => 'feed', 30 => 'author_name', 31 => 'pagename', 32 => 'page_id', 33 => 'error', 34 => 'attachment', 35 => 'attachment_id', 36 => 'subpost', 37 => 'subpost_id', 38 => 'preview', 39 => 'robots', 40 => 'favicon', 41 => 'taxonomy', 42 => 'term', 43 => 'cpage', 44 => 'post_type', 45 => 'embed', 46 => 'post_format', 47 => 'rest_route', 48 => 'sitemap', 49 => 'sitemap-subtype', 50 => 'sitemap-stylesheet', 51 => 'entries', 52 => 'pdf', 53 => 'sitemap', 54 => 'sitemap_n', 55 => 'yoast-sitemap-xsl']; public $private_query_vars = [0 => 'offset', 1 => 'posts_per_page', 2 => 'posts_per_archive_page', 3 => 'showposts', 4 => 'nopaging', 5 => 'post_type', 6 => 'post_status', 7 => 'category__in', 8 => 'category__not_in', 9 => 'category__and', 10 => 'tag__in', 11 => 'tag__not_in', 12 => 'tag__and', 13 => 'tag_slug__in', 14 => 'tag_slug__and', 15 => 'tag_id', 16 => 'post_mime_type', 17 => 'perm', 18 => 'comments_per_page', 19 => 'post__in', 20 => 'post__not_in', 21 => 'post_parent', 22 => 'post_parent__in', 23 => 'post_parent__not_in', 24 => 'title', 25 => 'fields']; public $extra_query_vars = []; public $query_vars = ['paged' => '2', 'tag' => 'ana-margarida-cunha', 'pdf' => '9370']; public $query_string = 'paged=2&tag=ana-margarida-cunha&pdf=9370'; public $request = 'tag/ana-margarida-cunha/page/2'; public $matched_rule = 'tag/([^/]+)/page/?([0-9]{1,})/?$'; public $matched_query = 'tag=ana-margarida-cunha&paged=2'; public $did_permalink = TRUE } )...\PDFModule.php:27
101.890184668592Dinamiko\DKPDF\PDF\Generator->generate_pdf( )...\Generator.php:40
112.026895689128Dinamiko\DKPDF\PDF\Generator->add_content_to_mpdf( $mpdf = class Dinamiko\DKPDF\Vendor\Mpdf\Mpdf { public $useFixedNormalLineHeight = FALSE; public $useFixedTextBaseline = FALSE; public $adjustFontDescLineheight = 1.14; public $interpolateImages = FALSE; public $defaultPagebreakType = 'cloneall'; public $indexUseSubentries = TRUE; public $autoScriptToLang = FALSE; public $baseScript = 1; public $autoVietnamese = TRUE; public $autoArabic = TRUE; public $CJKforceend = FALSE; public $h2bookmarks = []; public $h2toc = []; public $decimal_align = ['DP' => '.', 'DC' => ',', 'DM' => '·', 'DA' => '٫', 'DD' => '-']; public $margBuffer = 2; public $splitTableBorderWidth = 0; public $bookmarkStyles = []; public $useActiveForms = FALSE; public $repackageTTF = FALSE; public $allowCJKorphans = TRUE; public $allowCJKoverflow = FALSE; public $useKerning = FALSE; public $restrictColorSpace = 0; public $bleedMargin = 5; public $crossMarkMargin = 5; public $cropMarkMargin = 8; public $cropMarkLength = 18; public $nonPrintMargin = 8; public $PDFX = FALSE; public $PDFXauto = FALSE; public $PDFA = FALSE; public $PDFAversion = '1-B'; public $PDFAauto = FALSE; public $ICCProfile = ''; public $printers_info = FALSE; public $iterationCounter = FALSE; public $smCapsScale = 0.75; public $smCapsStretch = 110; public $backupSubsFont = [0 => 'dejavusanscondensed', 1 => 'freesans', 2 => 'sun-exta']; public $backupSIPFont = 'sun-extb'; public $fonttrans = ['times' => 'timesnewroman', 'courier' => 'couriernew', 'trebuchet' => 'trebuchetms', 'comic' => 'comicsansms', 'franklin' => 'franklingothicbook', 'ocr-b' => 'ocrb', 'ocr-b10bt' => 'ocrb', 'damase' => 'mph2bdamase']; public $debugfonts = FALSE; public $useAdobeCJK = FALSE; public $percentSubset = 30; public $maxTTFFilesize = 2000; public $BMPonly = [0 => 'dejavusanscondensed', 1 => 'dejavusans', 2 => 'dejavuserifcondensed', 3 => 'dejavuserif', 4 => 'dejavusansmono']; public $tableMinSizePriority = FALSE; public $dpi = 96; public $watermarkImgAlphaBlend = 'Normal'; public $watermarkImgBehind = FALSE; public $justifyB4br = FALSE; public $packTableData = FALSE; public $pgsIns = []; public $simpleTables = FALSE; public $enableImports = FALSE; public $debug = FALSE; public $setAutoTopMargin = FALSE; public $setAutoBottomMargin = FALSE; public $autoMarginPadding = 2; public $collapseBlockMargins = TRUE; public $falseBoldWeight = 5; public $normalLineheight = 1.33; public $incrementFPR1 = 10; public $incrementFPR2 = 20; public $incrementFPR3 = 30; public $incrementFPR4 = 50; public $SHYlang = 'en'; public $SHYleftmin = 2; public $SHYrightmin = 2; public $SHYcharmin = 2; public $SHYcharmax = 10; public $SHYlanguages = [0 => 'en', 1 => 'de', 2 => 'es', 3 => 'fi', 4 => 'fr', 5 => 'it', 6 => 'nl', 7 => 'pl', 8 => 'ru', 9 => 'sv']; public $pagenumPrefix = ''; public $pagenumSuffix = ''; public $nbpgPrefix = ''; public $nbpgSuffix = ''; public $showImageErrors = FALSE; public $allow_output_buffering = FALSE; public $autoPadding = FALSE; public $tabSpaces = 8; public $autoLangToFont = FALSE; public $watermarkTextAlpha = 0.2; public $watermarkImageAlpha = 0.2; public $watermark_size = NULL; public $watermark_pos = NULL; public $annotSize = 0.5; public $annotMargin = NULL; public $annotOpacity = 0.5; public $title2annots = FALSE; public $keepColumns = FALSE; public $keep_table_proportions = TRUE; public $ignore_table_widths = FALSE; public $ignore_table_percents = FALSE; public $list_number_suffix = '.'; public $list_auto_mode = 'browser'; public $list_indent_first_level = 0; public $list_indent_default = '40px'; public $list_indent_default_mpdf = '0em'; public $list_marker_offset = '5.5pt'; public $list_symbol_size = '3.6pt'; public $useSubstitutions = FALSE; public $CSSselectMedia = 'print'; public $forcePortraitHeaders = FALSE; public $forcePortraitMargins = FALSE; public $displayDefaultOrientation = FALSE; public $ignore_invalid_utf8 = FALSE; public $allowedCSStags = 'DIV|P|H1|H2|H3|H4|H5|H6|FORM|IMG|A|BODY|TABLE|HR|THEAD|TFOOT|TBODY|TH|TR|TD|UL|OL|LI|PRE|BLOCKQUOTE|ADDRESS|DL|DT|DD|ARTICLE|ASIDE|FIGURE|FIGCAPTION|FOOTER|HEADER|HGROUP|NAV|SECTION|MAIN|MARK|DETAILS|SUMMARY|METER|PROGRESS|TIME|SPAN|TT|I|B|BIG|SMALL|EM|STRONG|DFN|CODE|SAMP|KBD|VAR|CITE|ABBR|ACRONYM|STRIKE|S|U|DEL|INS|Q|FONT|SELECT|INPUT|TEXTAREA|CAPTION|FIELDSET|LEGEND|TEXTCIRCLE|DOTTAB|BDO|BDI'; public $onlyCoreFonts = FALSE; public $allow_charset_conversion = TRUE; public $jSWord = 0.4; public $jSmaxChar = 2; public $jSmaxCharLast = 1; public $jSmaxWordLast = 2; public $max_colH_correction = 1.15; public $table_error_report = FALSE; public $table_error_report_param = ''; public $biDirectional = FALSE; public $text_input_as_HTML = FALSE; public $anchor2Bookmark = 0; public $shrink_tables_to_fit = 1.4; public $allow_html_optional_endtags = TRUE; public $img_dpi = 96; public $whitelistStreamWrappers = [0 => 'http', 1 => 'https', 2 => 'file']; public $defaultheaderfontsize = 8; public $defaultheaderfontstyle = 'BI'; public $defaultheaderline = 1; public $defaultfooterfontsize = 8; public $defaultfooterfontstyle = 'BI'; ... } )...\Generator.php:49
122.036795636040Dinamiko\DKPDF\Vendor\Mpdf\Mpdf->WriteHTML( $html = '<html>\n<head>\n <link type="text/css" rel="stylesheet" href="https://events.ipv.pt/cidei/wp-content/themes/astra/style.css"\n media="all"/>\n <style>\n a, code, ins, kbd, tt {background-color: transparent;}\n\n .custom-fields-section {\n margin-top: 20px;\n padding-top: 15px;\n border-top: 1px solid #ddd;\n }\n\n .custom-fields-section h3 {\n margin: 0 0 10px 0;\n font-size: 16px;\n font-weight: bold;\n }\n\n '..., $mode = ???, $init = ???, $close = ??? )...\Generator.php:282
132.063697010448Dinamiko\DKPDF\Vendor\Mpdf\Tag->OpenTag( $tag = 'ARTICLE', $attr = ['ID' => 'POST-9370', 'CLASS' => 'POST-9370 POST TYPE-POST STATUS-PUBLISH FORMAT-STANDARD HAS-POST-THUMBNAIL HENTRY CATEGORY-COMPETITIVO CATEGORY-CONCLUIDO CATEGORY-EDUCACAO-PARA-A-SAUDE-E-QUALIDADE-DE-VIDA CATEGORY-NACIONAL CATEGORY-PROJETO TAG-2020-2023 TAG-ANA-MARGARIDA-CUNHA AST-ARTICLE-SINGLE'], $ahtml = [0 => ' ', 1 => 'main id="primary" class="site-main"', 2 => ' ', 3 => 'article id="post-9370" class="post-9370 post type-post status-publish format-standard has-post-thumbnail hentry category-competitivo category-concluido category-educacao-para-a-saude-e-qualidade-de-vida category-nacional category-projeto tag-2020-2023 tag-ana-margarida-cunha ast-article-single"', 4 => ' ', 5 => 'header class="entry-header"', 6 => ' ', 7 => 'h1 class="entry-title"', 8 => 'PT/FB/BL-2018-331 | Frontostriatal neurophysiological underpins of decision-making', 9 => '/h1', 10 => ' ', 11 => '/header', 12 => ' ', 13 => 'div class="entry-content"', 14 => ' ', 15 => 'div class="RowArticle contBoxArt"', 16 => ' ', 17 => 'div class="columnArt1"', 18 => ' ', 19 => 'p', 20 => '', 21 => 'strong', 22 => 'Duration: 2020 – 2023', 23 => '/strong', 24 => '', 25 => '/p', 26 => ' ', 27 => 'h5', 28 => 'Principal Researcher', 29 => '/h5', 30 => ' ', 31 => 'p', 32 => '', 33 => '/p', 34 => ' ', 35 => 'p style="margin-top: -20px;"', 36 => '', 37 => 'strong', 38 => 'Hugo Leite-Almeida', 39 => '/strong', 40 => '', 41 => '/p', 42 => ' ', 43 => 'p', 44 => '', 45 => '/p', 46 => ' ', 47 => 'h5', 48 => 'Team Members', 49 => '/h5', 50 => ' ', 51 => 'p', 52 => '', 53 => '/p', 54 => ' ', 55 => 'p style="margin-top: -20px;"', 56 => '', 57 => 'strong', 58 => 'Ana Margarida Cunha', 59 => '/strong', 60 => '', 61 => '/p', 62 => ' ', 63 => 'p', 64 => '', 65 => '/p', 66 => ' ', 67 => 'p', 68 => '', 69 => 'strong', 70 => 'Research Line: ', 71 => '/strong', 72 => '', 73 => 'br /', 74 => 'Health Education and Quality of Life', 75 => '/p', 76 => ' ', 77 => 'p', 78 => '', 79 => '/p', 80 => ' ', 81 => 'h5', 82 => 'Funding', 83 => '/h5', 84 => ' ', 85 => 'p', 86 => '', 87 => '/p', 88 => ' ', 89 => 'p style="margin-top: -20px;"', 90 => 'Fundação Bial', 91 => '/p', 92 => ' ', 93 => 'p', 94 => '', 95 => '/p', 96 => ' ', 97 => 'p', 98 => '', 99 => 'a class="bt_quad" href="https://icvs.uminho.pt/project/frontostriatal-neurophysiological-underpins-of-decision-making/" rel="noopener" target="_blank"', 100 => 'more', 101 => '/a', 102 => '', 103 => '/p', 104 => ' ', 105 => 'p', 106 => '', 107 => '/p', 108 => ' ', 109 => '/div', 110 => ' ', 111 => 'div class="columnArt2"', 112 => ' Animals perform thousands of daily decisions, some requiring assessment of risks, future gains/losses, while many others simply rely on habits. Decision-making deficits are a common feature of many neuropsychiatric diseases as obsessive-compulsive disorder but can also manifest in chronic pain or in chronic stress conditions.', 113 => 'br /', 114 => 'Decision-making is a multi-dimensional process including timing, inhibition, attentional set-shifting and risk assessment, thus involving a complex network. Frontostriatal nodes are known to be of the uttermost importance in these processes as revealed by many clinical and preclinical studies in both normal and disease conditions. Notably, the medial prefrontal (mPFC)and orbitofrontal cortices (OFC), dorsal striatum (Str) and nucleus accumbens (NAcc) have wellstablished roles in inhibition, outcome value up'..., 115 => 'br /', 116 => 'Recently, we observed that before decision-making, the activity of the mPFC, OFC, Str and NAcc was markedly different if the outcome, 3 seconds later, was a timed or an impulsive decision in the variable delay-to-signal task (VDS). Interestingly, as time elapsed and decision approached, most of these differences in activity disappear and synchrony between the mPFC, more specifically the prelimbic (Prl) region in both hemispheres and OFC and NAcc emerged differentiating timed and impulsive decision-making. W'..., 117 => 'br /', 118 => 'In this project we will depart from this set of data aiming to attend to the following questions:', 119 => 'br /', 120 => 'i. how comparable is frontostriatal network activity in different decision-making domains, specifically VDS (impulsivity) and attentional set-shifting task (ASST; stimulus selection and cognitive flexibility)?', 121 => 'br /', 122 => 'ii. what is the role of each node during the time window of decision i.e. how do the nodes sequentially interact until the behavioral outcome?', 123 => 'br /', 124 => 'iii. what is the impact of a targeted shutdown of one of the network’s node/area in behavior', 125 => 'br /', 126 => 'iv. and how does the network compensate?', 127 => 'br /', ...], $ihtml = 3 )...\Mpdf.php:13921
142.063997012736Dinamiko\DKPDF\Vendor\Mpdf\Tag\BlockTag->open( $attr = ['ID' => 'POST-9370', 'CLASS' => 'POST-9370 POST TYPE-POST STATUS-PUBLISH FORMAT-STANDARD HAS-POST-THUMBNAIL HENTRY CATEGORY-COMPETITIVO CATEGORY-CONCLUIDO CATEGORY-EDUCACAO-PARA-A-SAUDE-E-QUALIDADE-DE-VIDA CATEGORY-NACIONAL CATEGORY-PROJETO TAG-2020-2023 TAG-ANA-MARGARIDA-CUNHA AST-ARTICLE-SINGLE'], $ahtml = [0 => ' ', 1 => 'main id="primary" class="site-main"', 2 => ' ', 3 => 'article id="post-9370" class="post-9370 post type-post status-publish format-standard has-post-thumbnail hentry category-competitivo category-concluido category-educacao-para-a-saude-e-qualidade-de-vida category-nacional category-projeto tag-2020-2023 tag-ana-margarida-cunha ast-article-single"', 4 => ' ', 5 => 'header class="entry-header"', 6 => ' ', 7 => 'h1 class="entry-title"', 8 => 'PT/FB/BL-2018-331 | Frontostriatal neurophysiological underpins of decision-making', 9 => '/h1', 10 => ' ', 11 => '/header', 12 => ' ', 13 => 'div class="entry-content"', 14 => ' ', 15 => 'div class="RowArticle contBoxArt"', 16 => ' ', 17 => 'div class="columnArt1"', 18 => ' ', 19 => 'p', 20 => '', 21 => 'strong', 22 => 'Duration: 2020 – 2023', 23 => '/strong', 24 => '', 25 => '/p', 26 => ' ', 27 => 'h5', 28 => 'Principal Researcher', 29 => '/h5', 30 => ' ', 31 => 'p', 32 => '', 33 => '/p', 34 => ' ', 35 => 'p style="margin-top: -20px;"', 36 => '', 37 => 'strong', 38 => 'Hugo Leite-Almeida', 39 => '/strong', 40 => '', 41 => '/p', 42 => ' ', 43 => 'p', 44 => '', 45 => '/p', 46 => ' ', 47 => 'h5', 48 => 'Team Members', 49 => '/h5', 50 => ' ', 51 => 'p', 52 => '', 53 => '/p', 54 => ' ', 55 => 'p style="margin-top: -20px;"', 56 => '', 57 => 'strong', 58 => 'Ana Margarida Cunha', 59 => '/strong', 60 => '', 61 => '/p', 62 => ' ', 63 => 'p', 64 => '', 65 => '/p', 66 => ' ', 67 => 'p', 68 => '', 69 => 'strong', 70 => 'Research Line: ', 71 => '/strong', 72 => '', 73 => 'br /', 74 => 'Health Education and Quality of Life', 75 => '/p', 76 => ' ', 77 => 'p', 78 => '', 79 => '/p', 80 => ' ', 81 => 'h5', 82 => 'Funding', 83 => '/h5', 84 => ' ', 85 => 'p', 86 => '', 87 => '/p', 88 => ' ', 89 => 'p style="margin-top: -20px;"', 90 => 'Fundação Bial', 91 => '/p', 92 => ' ', 93 => 'p', 94 => '', 95 => '/p', 96 => ' ', 97 => 'p', 98 => '', 99 => 'a class="bt_quad" href="https://icvs.uminho.pt/project/frontostriatal-neurophysiological-underpins-of-decision-making/" rel="noopener" target="_blank"', 100 => 'more', 101 => '/a', 102 => '', 103 => '/p', 104 => ' ', 105 => 'p', 106 => '', 107 => '/p', 108 => ' ', 109 => '/div', 110 => ' ', 111 => 'div class="columnArt2"', 112 => ' Animals perform thousands of daily decisions, some requiring assessment of risks, future gains/losses, while many others simply rely on habits. Decision-making deficits are a common feature of many neuropsychiatric diseases as obsessive-compulsive disorder but can also manifest in chronic pain or in chronic stress conditions.', 113 => 'br /', 114 => 'Decision-making is a multi-dimensional process including timing, inhibition, attentional set-shifting and risk assessment, thus involving a complex network. Frontostriatal nodes are known to be of the uttermost importance in these processes as revealed by many clinical and preclinical studies in both normal and disease conditions. Notably, the medial prefrontal (mPFC)and orbitofrontal cortices (OFC), dorsal striatum (Str) and nucleus accumbens (NAcc) have wellstablished roles in inhibition, outcome value up'..., 115 => 'br /', 116 => 'Recently, we observed that before decision-making, the activity of the mPFC, OFC, Str and NAcc was markedly different if the outcome, 3 seconds later, was a timed or an impulsive decision in the variable delay-to-signal task (VDS). Interestingly, as time elapsed and decision approached, most of these differences in activity disappear and synchrony between the mPFC, more specifically the prelimbic (Prl) region in both hemispheres and OFC and NAcc emerged differentiating timed and impulsive decision-making. W'..., 117 => 'br /', 118 => 'In this project we will depart from this set of data aiming to attend to the following questions:', 119 => 'br /', 120 => 'i. how comparable is frontostriatal network activity in different decision-making domains, specifically VDS (impulsivity) and attentional set-shifting task (ASST; stimulus selection and cognitive flexibility)?', 121 => 'br /', 122 => 'ii. what is the role of each node during the time window of decision i.e. how do the nodes sequentially interact until the behavioral outcome?', 123 => 'br /', 124 => 'iii. what is the impact of a targeted shutdown of one of the network’s node/area in behavior', 125 => 'br /', 126 => 'iv. and how does the network compensate?', 127 => 'br /', ...], $ihtml = 3 )...\Tag.php:240
152.063997012768Dinamiko\DKPDF\Vendor\Mpdf\CssManager->PreviewBlockCSS( $tag = 'ARTICLE', $attr = ['ID' => 'POST-9370', 'CLASS' => 'POST-9370 POST TYPE-POST STATUS-PUBLISH FORMAT-STANDARD HAS-POST-THUMBNAIL HENTRY CATEGORY-COMPETITIVO CATEGORY-CONCLUIDO CATEGORY-EDUCACAO-PARA-A-SAUDE-E-QUALIDADE-DE-VIDA CATEGORY-NACIONAL CATEGORY-PROJETO TAG-2020-2023 TAG-ANA-MARGARIDA-CUNHA AST-ARTICLE-SINGLE'] )...\BlockTag.php:37